Sellest on küll üle 4 aasta möödas, aga laias plaanis võib selle osaga siiani veel asja kokku võtta ju küll:
Sugar substitutes in various food and beverages are very popular in most of the countries. Extensive scientific research has demonstrated the SAFETY of the six low-calorie sweeteners currently approved for use in foods in the U.S. and Europe (stevia, acesulfame-K, aspartame, neotame, saccharin and sucralose) each with an acceptable daily intake. A number of studies have been carried out to confirm the safety of artificial sweeteners. A number of studies have also shown the adverse effects of the same. But most of the studies have limitations such as effects shown only in ANIMALS not in human, SMALL SAMPLE SIZE, HIGH doses, statistically non-significant or borderline significant, etc. The sugar substitutes are thoroughly investigated for safety with hundreds of scientific studies and then approved by different regulatory authorities like the U.S. FDA, JECFA and FSANZ. Some agents are approved with warning labels too. So further exploration is required with well-designed large-scale studies in the general population. On the ANECDOTAL evidence, it has been concluded that based on analysis of the database of case histories, there are a number of symptoms that are recurrently reported by individuals who BELIEVE that they are caused by sugar substitute ingestion.